Epigenetic remodeling of the fungal secondary metabolome.
نویسندگان
چکیده
Fungi treated with DNA methyltransferase and histone deacetylase inhibitors exhibited natural product profiles with enhanced chemical diversity demonstrating that small-molecule epigenetic modifiers are effective tools for rationally controlling the native expression of fungal biosynthetic pathways and generating new biomolecules.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 6 11 شماره
صفحات -
تاریخ انتشار 2008